Figure 10
Effect of acute respiratory distress syndrome (ARDS) on interleukin-36γ (IL-36γ) induction in humans. IL-36γ protein was assessed in both plasma (a) and bronchoalveolar lavage (BALF) (b) of humans with ARDS due to bacterial pneumonia compared with health control subjects (P<0.05 compared with control by one-way analysis of variance (ANOVA) with Dunnett’s multiple comparisons test, n=8–40 patients per time point). (c) Alveolar macrophages were isolated from seven patients within the first week of onset of ARDS and analyzed for IL-36γ mRNA (*P<0.05 compared with control by Student’s t-test, n=5–7 patients per group).
