Figure 2
Effect of interleukin-36γ (IL-36γ) on mortality during pneumococcal pneumonia. (a) Wild-type (WT) and IL-36γ−/− mice were infected with intrathecal (i.t.) Streptococcus pneumoniae (Sp) and observed. (*P<0.05, n=11 mice per group, combined from two separate experiments). (b) Animals were passively immunized with either a control immunoglobulin G (IgG) or an anti-IL-36γ IgG and then infected with i.t. Sp. (*P<0.05 by Mantel–Cox test, n=8 mice per group, combined from two separate experiments).
