Figure 3
Altered gut microbiota associates with “Complications” subgroup and IgA levels in patients with common variable immunodeficiency (CVID). (a) Microbial alpha diversity (Chao1) in the “Infection only”, “Complications”, Controls, and inflammatory bowel disease (IBD) groups. (b) Dysbiosis index in the “Infection only”, “Complications”, and Controls. (c) Alpha diversity in the CVID patients with IgA<0.1 g/l versus IgA≥0.1 g/l. All the figures are shown in median, quartiles, and range. The comparisons are made by Mann–Whitney U test in panel (a) and (b), and t-test in panel (c). Significant P-values are marked as ***P<0.001, **P<0.01, *P<0.05.
