Figure 5
Elevated markers of monocyte and T-cell activation in CVID associates with alpha diversity and dysbiosis index. (a) Plasma levels of circulating soluble CD14 (sCD14) in CVID patients and controls showed in median, quartiles, and range. (b) Plasma levels of soluble CD25 (sCD25) in CVID patients and controls showed in median, quartiles, and range. (c) Correlation of sCD25 versus alpha diversity (Chao1) (d) Correlation of sCD25 versus dysbiosis index. (e) Plasma sCD14 in the “Infection only”, “Complications”, and Controls groups. (f) Plasma sCD25 in the “Infection only”, “Complications”, and Controls groups. (g) Correlation of % naive CD4 and alpha diversity (Chao1). Comparisons are made by Mann–Whitney U test or Spearman’s rank correlation test, as appropriate. Significant P-value is marked as ***P<0.001, **P<0.01, *P<0.05. Rho refers to Spearman’s rank correlation coefficient.
