Figure 4

Maintenance of CD4 memory is IL-15 independent. B6 wild-type (WT) and IL-15 deficient (IL-15 knockout (KO)) mice were orally infected with InlAM rLm and LLO-specific CD4 T-cell populations were examined in the spleen, MLN, LP, and IEL for frequency (a) and number (b) at the indicated times after infection. Data are representative of two to four individual time course experiments with three to eight mice per time point and depict the mean±s.e.m. *P<0.05, **P<0.01 (unpaired Student’s t-test).