Figure 6
Heatmap representation of changes in expression of selected immune-related transcripts, mRNA signatures associated with eosinophils or neutrophils, and nasosorption cytokines. (a) Response to nasal allergen challenge (NAC) alone (upper) with baseline interleukin (IL)-33 mRNA expression appearing in a separate column on the left of a. (b) NAC preceded by single 25 mg dose of prednisone (lower). Magenta represents upregulation, whereas cyan represents downregulation. “Eosinophil” and “neutrophil” refer to mRNA-derived cell-type composite markers (Supplementary Table E5 and Figure 3b). Horizontal dashed yellow line separates responders “R” from non-responders “NR”. Vertical dashed yellow lines separate categories of analytes. White boxes signify missing values.
