Figure 6 | Mucosal Immunology

Figure 6

From: Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation

Figure 6

We observed a significant reduction in the abundance of OTUs associated with the genera (a) Lactobacillus and (b) Clostridium in morphine-treated mice. These genera have been strongly implicated in deconjugation of secondary bile acids, enabling their reabsorption through hepatoenteric circulation. Ntx, naltrexone; OTU, operational taxonomic unit. ‘***’ denotes highly significant differences with exact P-value provided at the bottom of each panel.

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