Figure 3
Itln contributes to HDM-induced Il-25, Il-33, and Tslp expression in mouse lungs. (a–d) The kinetics of Itln1, Il-25, Il-33, and Tslp expression in the lungs of WT mice after airway exposure to HDM were determined by quantitative PCR. n=6 mice per group. Data are mean±s.e.m. *P<0.05 vs. WT treated with vehicle. (e–h) The expression of Itln1, Il-25, Il-33, and Tslp in Itln KD mice and WT mice after airway exposure to HDM for 2 h were determined by quantitative PCR. *P<0.05; **P<0.01; ***P<0.001 vs. WT mice exposed to HDM for 2 h. Results are representative of three independent experiments.
