Figure 5
Resolvin D1 is organ protective in chronic P. aeruginosa infection and enhances non phlogistic clearance of P. aeruginosa and inflammatory cells by macrophages. Histopathology and semiquantitative scores of (a) inflammation and mucous metaplasia and (b) bronchiolar epithelial hyperplasia of lung sections collected at 21 DPI from infected mice receiving vehicle or RvD1 (100 ng/mouse) every 48 h from day 5 following inoculum. Photomicrographs are representative from 5 mice/group. Semiquantitative scores are mean±s.e.m. from two experiments with five mice/group. *P<0.05; **P<0.01; ***P<0.001.
