Figure 6
From: IL-33 promotes gastrointestinal allergy in a TSLP-independent manner
Intradermal administration of interleukin (IL)-33 promotes gastrointestinal (GI) allergy. (a) Experimental protocol. (b) Representative photograph of the cecum and colon from indicated mice. (c) Diarrhea occurrence. (d) Diarrhea score. (e) ovalbumin (OVA)-specific IgE. (f) Intracellular cytokine staining of mesenteric lymph node (MLN) cells isolated from mice treated with phosphate-buffered saline (PBS)+OVA (upper) and IL-33+OVA (lower). Plots are gated on CD4+CD44hi cells. (g) Mouse MCPT-1 (mMCP-1) serum levels. Data are representative of two independent experiments with three to four mice per group. Error bars indicate the mean±s.d. ***P≤0.001.
