Table 1 Active anion secretion in C. jejuni-infected mucosa and controls

From: Campylobacter jejuni impairs sodium transport and epithelial barrier function via cytokine release in human colon

 

ISC (μmol h−1 cm−2)

ΔISC (μmol h−1 cm−2)

n

 

Basal

Basal

After PGE 2 +theophylline

After carbachol

After bumetanide

 
 

Uncorrected values

Corrected values with R t /R epi

Corrected values with R t /R epi

 

Control

4.9±1.2

6.4±1.5

5.0±1.0

9.3±1.6

1.3±0.3

6

C. jejuni

2.0±0.2

3.2±0.4

1.9±0.6

3.7±1.9

1.5±0.4

6

P.

<0.05

n.s.

<0.05

<0.05

n.s.

 
  1. Abbreviations: n.s., not significant; PGE2, prostaglandin E2.
  2. Data represent mean±s.e.m. Student’s t-test. Short-circuit currents (ISC) were corrected for Rt/Repi. Whenever the ratio of Rt over Repi becomes significantly different, active transport parameters as ISC need to be corrected, which follows the same principle like the correction of ISC for the bath resistance (see also Supplementary Methods). In the C. jejuni-infected group, Rt/Repi was 1.63±0.10 and thus higher than in the control group with 1.29±0.08 (n=6 each, P<0.05).
PowerPoint slide
Back to article page