Figure 2

Nanowires and nanotubes for intracellular measurement. (a) A kinked silicon nanowire was used to form a 3D FET device for direct measurement of intracellular potentials. Reproduced with permission from Ref. 20. (b) Vertical electrode arrays based on silicon nanowires. Left: SEM image of nine vertical nanowire electrodes. Right: SEM image of a rat cortical cell on top of a vertical nanowire electrode array pad. Reproduced with permission from Ref. 33. (c) Multifunctional carbon nanotube endoscope in which the carbon nanotubes cause less damage to the cell structure than glass micropipettes with conical tips. Reproduced with permission from Ref. 34. (d) A SnO2 nanowire was fabricated on an optical fiber for intracellular optical measurement. Reproduced with permission from Ref. 35.