Table 3 Multivariate survival analysis (Cox proportional hazards method) for patients with vertical growth phase melanoma of the nodular subtype, using tumor-related death as end point
From: Loss of BMI-1 expression is associated with clinical progress of malignant melanoma
Variables | Categories | N | HR a | 95% CI | P-valueb |
|---|---|---|---|---|---|
Clark's level of invasion | II, III, IV | 82 | 1 | ||
V | 24 | 2.5 | 1.3–4.9 | 0.006 | |
BMI-1 expression (6C9) | Strong | 27 | 1 | ||
Weak | 79 | 2.9 | 1.1–3.7 | 0.024 | |
p16 expression | Highc | 51 | 1 | ||
Low | 55 | 1.9 | 1.1–7.5 | 0.028 |
