Figure 1
From: Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum
Example of characteristic histologic pattern and immunophenotype of a juvenile secretory breast carcinoma. Secretory breast carcinoma with microacinar pattern (hematoxylin–eosin–saffron stains—HES, original magnification × 100, a). Tumor cells with abundant intracellular and extracellular secretory material (HES, original magnification × 200, b). Tumor cells with finely vacuolated cytoplasm and nuclei with nucleoli (HES, original magnification × 400, c). Immunohistochemical staining for S-100 (d), vimentin (e), EGFR (f), for CK5/6 (g), CK14 (i) and CK8/18 (h).
