Table 3 Immunophenotype and FISH results of six secretory breast carcinomas
From: Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum
Case | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 |
|---|---|---|---|---|---|---|
ER | 5% weak | 0% | 0% | 0% | 0% | 0% |
PR | 0% | 0% | 0% | 0% | 0% | 0% |
HER2 | 0% | 0% | 0% | 0% | 0% | 0% |
CK8/18 | 10% | 1% | 4% | 4% | 5% | 80% |
CK5/6 | 1% | 40% | 80% | 0% | 60% | 2% |
CK14 | 0% | 90% | 0% | 0% | 1% | 0% |
p63 | 0% | 0% | 0% | 0% | 0% | 0% |
SMA | 2% | 10% | 3% | 3% | 2% | 0% |
S100 | 100% | 100% | 0% | 100% | 100% | 100% |
Vimentin | 0% | 5% | 10% | 60% | 30% | 5% |
KIT | 3% | 0% | 0% | 1% | 5% | 1% |
EGFR | 100% moderate | 100% moderate | 0% | 0% | 0% | 15% moderate |
E-cadherin | 90% weak | 90% weak | 60% | 5% | 25% weak | 70% moderate |
ETV6 rearrangement | Present | Present | Present | Present | Present | Present |