Table 4 Immune response genes identified by SAM analysis to be significantly upregulated in CD8 positive tumors
Symbol | Name |
|---|---|
APOBEC3G | Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
B2M | β2-microglobulin |
BST2 | Bone marrow stromal cell antigen 2 |
C3 | Complement component 3 |
C4A | Complement component 4A (Rodgers blood group) |
C4B | Complement component 4B (Childo blood group) |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CFB | Complement factor B |
ISG15 | ISG15 ubiquitin-like modifier |
IFI6 | Interferon, α-inducible protein 6 |
GBP1 | Guanylate-binding protein 1, interferon-inducible, 67 kDa |
GBP2 | Guanylate-binding protein 2, interferon-inducible |
GBP3 | Guanylate-binding protein 3 |
HLA-A | Major histocompatibility complex, class I, A |
HLA-DMA | Major histocompatibility complex, class II, DM-α |
HLA-DMB | Major histocompatibility complex, class II, DM-β |
HLA-DPA1 | Major histocompatibility complex, class II, DP-α1 |
HLA-DPB1 | Major histocompatibility complex, class II, DP-β1 |
HLA-DQA2 | Major histocompatibility complex, class II, DQ-α2 |
HLA-DQB2 | Major histocompatibility complex, class II, DQ-β2 |
HLA-DRA | Major histocompatibility complex, class II, DR-α |
HLA-E | Major histocompatibility complex, class I, E |
HLA-F | Major histocompatibility complex, class I, F |
IFI27 | Interferon, α-inducible protein 27 |
IFI30 | Interferon, γ-inducible protein 30 |
IFI35 | Interferon-induced protein 35 |
IFIH1 | Interferon induced with helicase C domain 1 |
IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1 |
IFIT2 | Interferon-induced protein with tetratricopeptide repeats 2 |
IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 |
IL15 | Interleukin 15 |
IL32 | Interleukin 32 |
IL6R | Interleukin 6 receptor |
OAS1 | 2′,5′-Oligoadenylate synthetase 1, 40/46 kDa |
OAS2 | 2′-5′-Oligoadenylate synthetase 2, 69/71 kDa |
OAS3 | 2′-5′-Oligoadenylate synthetase 3, 100 kDa |
PSMB8 | Proteasome subunit, β-type, 8 |
PTPN22 | Protein tyrosine phosphatase, nonreceptor type 22 (lymphoid) |
RGS1 | Regulator of G-protein signaling 1 |
SECTM1 | Secreted and transmembrane 1 |
TAP1 | Transporter 1, ATP-binding cassette, subfamily B (MDR/TAP) |
TAP2 | Transporter 2, ATP-binding cassette, subfamily B (MDR/TAP) |
TNFSF10 | Tumor necrosis factor (ligand) superfamily, member 10 |
VAV1 | Vav 1 oncogene |
