Table 1 Advantages and disadvantages of UroVysion™ and ImmunoCyt/uCyt™

Advantages

 High sensitivity for high grade tumor

X

X

 High sensitivity for low grade tumor

X

 Detects occult lesions

X

X

 Predicts recurrence

X

X

 Not affected by BCG

X

 FDA-approved

X

X

 Detects upper tract tumor

X

X

Disadvantages

 Cytopathologist required

X

X

 Nonstandard criteria

X

 Time-consuming

X

X

 Requires fluorescence

X

X

 Requires 500 cells for negative

X

 Training required

X

X