Figure 1 | Modern Pathology

Figure 1

From: Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases

Figure 1

Example of direct sequencing of (a) KIT exon 13 and (b) KIT exon 17 mutant PCR amplification products in Case 13 and Case 10; single and double arrows indicate homozygous and heterozygous point mutations, respectively. Representative histological images of GISTs analyzed in this study. Benign spindle-cell GISTs (Case 20 and Case 3) with KIT exon 13 (c) and KIT exon 17 (d) mutations. Malignant spindle-cell GISTs (Case 10 and Case 6) with KIT exon 13 (e) and exon 17 (f) mutations. Malignant epithelioid GISTs (Case 14 and Case 12) with KIT exon 13 (g) and KIT exon 17 (h) mutations.

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