Table 1 Clinicopathologic features and p53 gene mutation status in patients with hepatocellular carcinoma
From: Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas
High-risk countries (n=24) | Low-risk country (n=33) | P-value | |
|---|---|---|---|
Mean age (years) | Unknown | 63.1 (range, 23–82) | NA |
Sex (male:female) | Unknown | 1.75:1 | NA |
Cirrhosis a | 0.2 | ||
With | 16 | 15 | |
Without | 7 | 17 | |
Hepatitis a | |||
Hepatitis B virus positive | 24 | 7 | 0.001 |
Hepatitis C virus positive | 0 | 3 | |
Alcoholic | 0 | 3 | |
Cryptogenic | 0 | 1 | |
Negative | 0 | 18 | |
p53 gene b | 0.004 | ||
Mutated | 12 | 3 | |
Wild type | 12 | 22 | |
