Figure 2
From: Recurrent numerical aberrations of JAK2 and deregulation of the JAK2-STAT cascade in lymphomas
(a) Expression of pJAK2 in follicular dendritic cells, endothelia and isolated lymphocytes of a reactive lymph node. Immunoperoxidase stain, 50 ×. (b) Expression of pSTAT3 in plasmocytoid/monocytoid sinus-associated lymphocytes of a reactive lymph node. Immunoperoxidase stain, 50 ×. (c) Expression of pSTAT5 in marginal zone lymphocytes surrounding a germinal center of a reactive lymph node. Immunoperoxidase stain, 200 ×. (d) Nuclear expression of pSTAT5 in a megakaryocyte of a polycythaemia vera patient with known high allelic JAK2 mutated/wild-type ratio. Immunoperoxidase stain, 400 ×. (e) Striking nuclear positivity for pSTAT5 in K562 cell pellets. Immunoperoxidase stain, 300 ×.
