Figure 2 | Modern Pathology

Figure 2

From: Actinin-4 gene amplification in ovarian cancer: a candidate oncogene associated with poor patient prognosis and tumor chemoresistance

Figure 2

Representative immunohistochemistry for actinin-4 protein in ovarian cancers. (a) A case of clear-cell adenocarcinoma showing low actinin-4 expression. Cases showing high cytoplasmic and/or membranous actinin-4 expression with a histology of (b) serous adenocarcinoma; (c) clear-cell adenocarcinoma; and (d) mucinous adenocarcinoma. Note the immunoreactivity in capillary endothelial cells (arrowheads in a and b) for comparison with that in tumor cells. Original magnification: × 400 in (a, c); × 200 in (b, d).

Back to article page