Figure 2 | Modern Pathology

Figure 2

From: Epigenetic instability is rare in fibrolamellar carcinomas but common in viral-associated hepatocellular carcinomas

Figure 2

The average number of methylated tumor suppressor gene promoters varies in association with underlying status of the background liver. The first column shows hepatocellular carcinomas associated with viral cirrhosis, the second column shows hepatocellular carcinoma arising in non-cirrhotic livers with no known underlying liver disease, while the third column shows primary fibrolamellar carcinomas and the fourth column metastatic fibrolamellar carcinoma. Differences that were statistically significant are shown by asterisks, *P<0.05; **P<0.001.

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