Figure 4 | Modern Pathology

Figure 4

From: Promoter hypermethylation and reduced expression of RASSF1A are frequent molecular alterations of endometrial carcinoma

Figure 4

MS-PCR for the RASSF1A gene in endometrial carcinoma and normal tissue. U, PCR product with primers specific for unmethylated DNA; M, PCR product with primers specific for methylated DNA. RASSF1A is methylated in the three cases of endometrial carcinoma. Notice that the degree of promoter hypermethylation differed between two different areas of one tumor (T1 and T2) of case 2.

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