Figure 3

Double immunofluorescence analysis showing stronger expression of perforin in CD8+ lymphocytes of medullary carcinoma (b) than those in invasive micropapillary carcinoma (a) and stronger expression of granzyme B in CD8+ lymphocytes of medullary carcinoma (d) than those in invasive micropapillary carcinoma (c). The green color indicates CD8-positive lymphocytes and the yellow color represents the perforin+CD8+ or granzyme B+CD8+ lymphocytes.