Figure 3
Immunohistochemical findings. (a) E-cadherin and (b) β-catenin were expressed at intercellular cell membranes of micropapillary tufts. (c) Laminin was found in the basement membrane of normal alveolar cells and in neoplastic cells in the main tumor, but was not found in cells constituting micropapillary tufts. (d) CD34-positive cells were enriched in the stroma of main tumor and the alveolar septum, whereas no CD34-positive cells were found in micropapillary tufts. (e) Cells constituting micropapillary tufts stained positive for Ki-67. (a) E-cadherin (b) β-catenin (c) Laminin (d) CD34 (e) Ki-67 × 40; inset: × 400.
