Figure 3 | Modern Pathology

Figure 3

From: Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms

Figure 3

(a) Spindle cell/pleomorphic lipoma, adipocytes with atypical nuclei admixed with ‘ropey’ collagen. (b) Polysomic MDM2/CEP12 FISH assay in a spindle cell/pleomorphic lipoma (same number of MDM2-red signals as CEP12-green signals). (c) Lipoma, adipocytes lacking atypia. (d) Lipoma with a negative MDM2/CEP12 FISH assay (two MDM2-red signals and two CEP12-green signals).

Back to article page