Table 1 GPC-3 staining results in benign and malignant hepatocellular lesions

From: Utility and limitations of glypican-3 expression for the diagnosis of hepatocellular carcinoma at both ends of the differentiation spectrum

Liver lesions

GPC-3 staining a

 

Total positive

Diffuse positive

Benign hepatocellular lesions

 Cirrhotic nodules (n=35)

4 (11)

0 (0)

 Macroregenerative nodule (n=10)

0 (0)

0 (0)

 Hepatic adenoma (n=8)

0 (0)

0 (0)

Borderline and malignant lesions

 High-grade dysplastic nodule (n=7)

3 (43)

0 (0)

 Extremely well-differentiated HCC (n=10)

5 (50)

2 (20)

 HCC, well differentiated (n=16)b

9 (56)

5 (31)

 HCC, moderately differentiated (n=18)

15 (83)

10 (56)

 HCC, poorly differentiated (n=24)

22 (89)

20 (83)

 Fibrolamellar HCC (n=11)

7 (64)

4 (36)

  1. HCC, hepatocellular carcinoma.
  2. aFigures in parenthesis reflect percentages.
  3. bIncludes extremely well-differentiated HCC.