Figure 1

FISH probes used to detect the genomic alteration in prostate cancer. (a) Location and names of the BAC probes spanning the genomic region of the ERG and TMPRSS2 loci at chromosome 21q22.2 and. The linear order and approximate distances of the BAC clones are based on the Human March 2006 assembly of the UCSC Genome Browser. (b) Genomic localization of the commercially available locus-specific PTEN probe and α-satellite DNA sequences of chromosome 10 probe (Vysis Inc.).