Table 4 Clinicopathological parameters from 47 of the 82 prostatic adenocarcinoma patients analyzed for the differential status of PTEN (deleted or not deleted) and presence of TMPRSS2:ERG fusions
TMPRSS2:ERG fusion and PTEN deletion | TMPRSS2:ERG not fused and PTEN not deleted | P-value | |
|---|---|---|---|
Preoperative PSA (ng/ml) a | 0.638 | ||
0.9–4.0 | 1 | 0 | |
4.0–10.0 | 10 | 14 | |
10.1–20.0 | 6 | 7 | |
20.1–84.0 | 4 | 3 | |
Median tumor volume (%) a | 0.309 | ||
0–10.0 | 4 | 10 | |
10.1–20.0 | 5 | 6 | |
20.1–85.0 | 13 | 11 | |
Gleason score | 0.308 | ||
4–6 | 12 | 16 | |
7 | 7 | 7 | |
8–9 | 4 | 1 | |
Pathologic stage | 0.743 | ||
pT2a | 1 | 1 | |
pT2b | 12 | 11 | |
pT3a | 6 | 9 | |
pT3b | 3 | 1 | |
pT4 | 1 | 2 | |
Seminal vesicle invasion a | 0.847 | ||
Negative | 18 | 22 | |
Positive | 2 | 2 | |
Perineural infiltration | 0.242 | ||
Negative | 2 | 5 | |
Positive | 21 | 19 | |
Angiolymphatic invasion a | 0.129 | ||
Negative | 17 | 17 | |
Positive | 5 | 5 | |
Extraprostatic extension | 0.587 | ||
Negative | 17 | 16 | |
Positive | 6 | 8 | |
Lymphonodal invasion a | 0.947 | ||
Negative | 21 | 20 | |
Positive | 1 | 1 |
