Table 2 Relationship of KRAS G>A transitions and MGMT promoter methylation

From: MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa

Molecular feature

Valid cases (%)

MGMT Meth (%)

MGMT Unmeth (%)

P-value, χ2

KRAS mutation type

358 (100)

   

G>A transitions

213 (59.5)

81 (59.1)

132 (59.7)

P=0.91

Other mutations

145 (40.5)

56 (40.9)

89 (40.3)

 
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