Table 1 Frequencies of TopoII α and HER2 amplification by multiplex ligation-dependent probe amplification analysis in 353 invasive breast cancer patients

From: Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer

Gene

Low level amplification (target/control ratio 1.5–2.0)

High level amplification (target/control ratio >2.0)

Total amplification

HER2

10/353 (3%)

34/353 (10%)

44/353 (13%)

TopoIIα

25/353 (7%)

8/353 (2%)

33/353 (9%)

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