Table 2 Comparison between multiplex ligation-dependent probe amplification (MLPA) and chromogenic in situ hybridization (CISH) results for TopoII α and HER2 on 284 breast cancer patients when a cut-off value of 1.5 between normal and low level amplified was applied

From: Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer

 

MLPA (cut-off=1.5)

 

Not amplified

Low level amplified

Amplified

Total

TopoIIα CISH

 Not amplified

249

20

0

269

 Low level amplified

2

4

2

8

 Amplified

0

1

6

7

HER2 CISH

 Not amplified

244

3

1

248

 Low level amplified

4

4

2

10

 Amplified

0

1

25

26

    

284

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