Table 3 Association between Topoisomerase IIα protein expression (by immunohistochemistry) and gene amplification status (by chromogenic in situ hybridization) in 265 invasive breast cancer patients (P=0.035)
Topoisomerase IIα protein | Total | ||
---|---|---|---|
Normal | Overexpressed | ||
TopoIIα not amplified | 144 | 107 | 251 |
TopoIIα amplified | 4 | 10 | 14 |