Table 3 Association between Topoisomerase IIα protein expression (by immunohistochemistry) and gene amplification status (by chromogenic in situ hybridization) in 265 invasive breast cancer patients (P=0.035)

From: Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer

 

Topoisomerase IIα protein

Total

 

Normal

Overexpressed

 

TopoIIα not amplified

144

107

251

TopoIIα amplified

4

10

14