Table 2 Distribution of molecular phenotypes and frequency of ER-β expression according to molecular phenotype

From: Estrogen receptor-β expression in invasive breast cancer in relation to molecular phenotype: results from the Nurses' Health Study

Molecular category

Frequency

ER-β+

ER-β−

Luminal A

1585/2170 (73%)

1140/1585 (72%)

445/1585 (28%)

Luminal B

115/2170 (5%)

78/115 (68%)

37/115 (32%)

HER2

125/2170 (6%)

69/125 (55%)

56/125 (45%)

Basal-like

240/2170 (11%)

144/240 (60%)

96/240 (40%)

Unclassified

105/2170 (5%)

50/105 (48%)

55/105 (52%)

  1. Luminal A, ER-α+ and/or PR+ and HER2–.
  2. Luminal B, ER-α + and/or PR+ and HER2+.
  3. HER2, ER-α– and PR– and HER2+.
  4. Basal-like, ER-α–, PR– and HER2– and cytokeratin 5/6+ and/or EGFR+.
  5. Unclassified, negative for ER, PR, HER2, cytokeratin 5/6 and EGFR.
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