Table 4 ER-β status according to tumor grade, tumor size, lymph node status and stage at diagnosis

From: Estrogen receptor-β expression in invasive breast cancer in relation to molecular phenotype: results from the Nurses' Health Study

Characteristic

ER-β+

ER-β−

P-value

Tumor gradea

  

<0.0001

 Grade 1

361/425 (85 %)

64/425 (15%)

 

 Grade 2

847/1190 (71%)

343/1190 (29%)

 

 Grade 3

260/530 (49%)

270/530 (51%)

 

Tumor size (cm)b

  

0.0008

 0.1–1.0

348/462 (75%)

114/462 (25%)

 

 1.1–2.0

536/788 (68%)

252/788 (32%)

 

 2.1–4.0

374/576 (65%)

202/576 (35%)

 

 4.1+

139/222 (63%)

83/222 (37%)

 

Lymph node statusb

  

0.06

 0 nodes

861/1242 (69%)

381/1242 (31%)

 

 1–3 nodes

282/423 (67%)

141/423 (33%)

 

 4–9 nodes

120/183 (66%)

63/183 (34%)

 

 10+ nodes

67/116 (58%)

49/116 (42%)

 

Stage at diagnosisb

  

0.10

 I/II

1145/1660 (69%)

515/1660 (31%)

 

 III/IV

259/400 (65%)

141/400 (35%)

 
  1. aData from centralized pathology review.
  2. bData abstracted from pathology report.