Table 3 Pathological characteristics of micropapillary ductal carcinoma in situ treated by breast-conserving surgery with and without ipsilateral recurrences
From: Micropapillary ductal carcinoma in situ of the breast: an inter-institutional study
Total (%) | ILRa (%) | NO ILRa (%) | P-value | Odds ratio | 95% Wald confidence limits | |
---|---|---|---|---|---|---|
36 (100) | 11 (31) | 25 (69) | ||||
Nuclear grade | ||||||
Low | 12 (33) | 2 (17) | 10 (83) | 1 | ||
Intermediate | 9 (25) | 1 (11) | 8 (89) | 0.041 | 0.62 | 0.04–8.20 |
High | 15 (42) | 8 (53) | 7 (47) | 5.71 | 0.92–35.47 | |
Nuclear grade | ||||||
Low/intermediate | 21 (58) | 3 (14) | 18 (86) | 0.025 | 1 | |
High | 15 (42) | 8 (53) | 7 (47) | 6.86 | 1.40–33.57 | |
Extent (mm) | ||||||
≤15 | 23 (64) | 6 (26) | 17 (74) | 1 | ||
16–39 | 7 (22) | 1 (14) | 6 (86) | 0.091 | 0.47 | 0.04–4.76 |
≥40 | 6 (14) | 4 (67) | 2 (33) | 5.67 | 0.82–39.26 | |
Necrosis | ||||||
No | 17 (47) | 5 (29) | 12 (71) | 0.887 | 1 | |
Yes | 19 (53) | 6 (32) | 13 (68) | 1.11 | 0.26–4.59 | |
Margin width (mm) | ||||||
>10 | 20 (56) | 5 (25) | 15 (75) | 1 | ||
1–9 | 12 (19) | 6 (50) | 6 (50) | 0.123 | 3.00 | 0.65–13.69 |
<1 | 4 (25) | 0 | 4 (100) | 0.31 | 0.01–6.81 | |
Microinvasion | ||||||
No | 31 (86) | 9 (29) | 22 (71) | 0.621 | 1 | |
Yes | 5 (14) | 2 (40) | 3 (60) | 1.63 | 0.23–11.45 | |
Van Nuys Prognostic Index | ||||||
1/2 | 30 (83) | 7 (23) | 23 (77) | 0.072 | 1 | |
3 | 6 (17) | 4 (67) | 2 (33) | 6.57 | 0.98–43.78 | |
Radiotherapy | ||||||
No | 13 (36) | 4 (31) | 9 (69) | 0.127 | 1 | |
Yes | 23 (64) | 7 (30) | 16 (70) | 0.98 | 0.22–4.30 |