Figure 2
From: Sarcomatoid mesothelioma: a clinical–pathologic correlation of 326 cases
Hematoxylin and eosin-stained sections (medium power) of pleural sarcomatoid malignant mesothelioma subtypes. (a) The sarcomatous pattern is characterized by a hypercellular spindle-cell neoplasm characterized by elongated nuclei, numerous mitotic figures, and eosinophilic cytoplasm. (b) Desmoplastic malignant mesothelioma is predominantly hypocellular with scattered atypical cells among dense collagenous tissue. (c) Osteosarcomatous pattern characterized by malignant cells with pleomorphic nuclei, numerous mitoses, and osteoid deposition. (d) The malignant fibrous histiocytoma-like pattern consists of markedly atypical cells with pleomorphic/giant-cell nuclei containing multiple nucleoli, abundant eosinophilic cytoplasm, and bizarre mitotic figures.
