Table 2 Comparisons of survivin expression between responders and nonresponders
From: Aberrant survivin expression in endometrial hyperplasia: another mechanism of progestin resistance
Preprogestin | Postprogestin | Post–pre difference | P-values | |
---|---|---|---|---|
Mean (range) | Mean (range) | Mean (s.d.) | ||
Responders | ||||
Epithelial cells index (range) | ||||
Nuclear | 78 (20–135) | 4 (0–25) | –74 (34.6) | <0.001 |
Cytoplasmic | 114 (70–200) | 14 (0–60) | −100 (42.9) | <0.001 |
Stromal cells index (range) | ||||
Nuclear | 18 (3–40) | 3 (0–15) | –15 (11.2) | 0.01 |
Cytoplasmic | 49 (0–90) | 10 (0–30) | −39 (28.5) | 0.02 |
Non-responders | ||||
Epithelial cells index (range) | ||||
Nuclear | 70 (30–135) | 75 (40–120) | 5 (42.9) | 0.8 |
Cytoplasmic | 128 (70–180) | 89 (50–110) | −39 (36.1) | 0.06 |
Stromal cells index (range) | ||||
Nuclear | 18 (7–30) | 12 (3–25) | −6 (8.7) | 0.2 |
Cytoplasmic | 56 (20–90) | 36 (20–70) | −20 (30.1) | 0.2 |