Figure 2
Desmocollin-3 and TTF-1 immunoreactivities in two poorly differentiated lung cancers reported as ‘NSCLC’ in cytological specimens. In the first case, the bronchoalveolar lavage (a) showed desmocollin-3 reactivity (b), in the absence of TTF-1 (c) in serial sections of the cell block; the case was subsequently diagnosed as poorly differentiated squamous carcinoma in the surgical specimen. The other case (d), which was histologically proven to be a large-cell carcinoma, did not contain any desmocollin-3 reactivity (e), but diffusely expressed TTF-1 (f) in serial sections of the cell block of the transthoracic fine-needle aspiration biopsy. (a, d: hematoxylin and eosin, original magnification × 200; b, c, e, f: immunoperoxidase for desmocollin-3 (b, e) and TTF-1 (c, f), original magnification × 200.)
