Figure 1

Immunohistochemistry for cyclin D1 (a) and p16 (b) within conventional tumor area. Cyclin D1 is most strongly expressed toward the peripheral aspect of the glands, whereas p16 staining is more marked centrally.
Immunohistochemistry for cyclin D1 (a) and p16 (b) within conventional tumor area. Cyclin D1 is most strongly expressed toward the peripheral aspect of the glands, whereas p16 staining is more marked centrally.