Table 2 FGFR 1, 2, 3 and 4 immunoreactivity in chordomas

From: Analysis of the fibroblastic growth factor receptor-RAS/RAF/MEK/ERK-ETS2/brachyury signalling pathway in chordomas

 

FGFR1

FGFR2

FGFR3

FGFR4

3 +++

17

8

13

4

++

0

0

0

1

+

0

1

0

0

2 +++

8

9

10

11

++

1

1

1

2

+

0

0

0

0

1 +++

1

17

15

15

++

0

1

0

2

+

1

3

0

0

0

22

10

11

15

Total number of positive cases

28/50

40/50

39/50

35/50

%

56%

80%

78%

70%

  1. The scoring system employed was as follows: negative immunoreactivity (0). Positive immunoreactivity includes the following subgroups: (1) ‘weak’, the intensity of the staining is less than the positive control, (2) ‘moderate’, the intensity of the staining is as strong as the positive control, and (3) ‘strong’, the intensity of the staining is stronger than the positive control. In addition, +, ++ and +++ indicate that < 5%, between 6 and 49%, and > 50%, respectively, of the lesional cells were immunoreactive.
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