Table 1 Results of MDM2 immunohistochemistry and FISH adjunctive tests on both well-differentiated liposarcomas/atypical lipomatous tumors and a variety of benign lipomatous neoplasms
Category | MDM2 + immunohistochemistry | MDM2 + FISH | No. of cases with autofluorescence |
|---|---|---|---|
Well-differentiated liposarcoma (n=17) | |||
Biopsy | 11/17 (65%) | 11/11 (100%) | 6 |
Resection | 15/17 (88%) | 16/17 (94%) | 0 |
Lipoma (n=11) | |||
Biopsy | 1/11 (9%) | 0/9 (0%) | 2 |
Resection | 1/11 (9%) | 0/11 (0%) | 0 |
Spindle cell/pleomorphic lipoma (n=2) | |||
Biopsy | 1/2 (50%) | 0/2 (0%) | 0 |
Resection | 0/2 (0%) | 0/2 (0%) | 0 |
Angiolipoma (n=10) | |||
Biopsy | 1/10 (10%) | 0/9 (0%) | 1 |
Resection | 0/10 (0%) | 0/8 (0%) | 2 |
Dedifferentiated liposarcoma (n=1) | |||
Biopsy | 1/1 (100%) | 1/1 (100%) | 0 |
Resection | 1/1 (100%) | 1/1 (100%) | 0 |
Myelolipoma (n=1) | |||
Biopsy | 0/1 (0%) | 0/1 (0%) | 0 |
Resection | 0/1 (0%) | 0/1 (0%) | 0 |
Intramuscular lipoma (n=8) | |||
Biopsy | 0/8 (0%) | 0/7 (0%) | 1 |
Resection | 0/8 (0%) | 0/8 (0%) | 0 |
Fibrolipoma (n=3) | |||
Biopsy | 0/3 (0%) | 0/3 (0%) | 0 |
Resection | 0/3 (0%) | 0/3 (0%) | 0 |
Lipoblastoma (n=1) | |||
Biopsy | 0/1 (0%) | 0/1 (0%) | 0 |
Resection | 0/1 (0%) | 0/1 (0%) | 0 |
Hibernoma (n=1) | |||
Biopsy | 1/1 (100%) | 0/0 (N/A) | 1 |
Resection | 0/1 (0%) | 0/0 (N/A) | 1 |
All benign lipomatous lesions (n=37) | |||
Biopsy | 4/37 (11%) | 0/32 (0%) | 5 |
Resection | 1/37 (3%) | 0/34 (0%) | 3 |
