Figure 1 | Modern Pathology

Figure 1

From: Breast carcinoma with amplified HER2: a gene expression signature specific for trastuzumab resistance and poor prognosis

Figure 1

Box plot of expression-detection P-value for all 42 samples. The expression-detection P-value is to test the null hypothesis of whether the expression intensity of a given gene is indistinguishable from the background intensity. Y axis: expression-detection P-value; X axis: samples (patients). Patient 11142 (shown in gray) stand out as an outlier showing majority of genes undetectable (large P-value). For data quality control, we filtered out this sample for further analysis. This led to 41 samples for further clinicopathologic and microarray data analysis.

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