Figure 5 | Modern Pathology

Figure 5

From: Breast carcinoma with amplified HER2: a gene expression signature specific for trastuzumab resistance and poor prognosis

Figure 5

Venn diagrams show little overlap for differentially expressed genes derived from different comparisons, including three groups, trastuzumab-treated, trastuzumab-non-treated and other. The latter group represents the unions of differentially expressed genes from the other six separate comparisons of clinicopathologic data (age, race, tumor stage, hormonal receptor status and menopause status). (a) Differentially expressed genes as defined by P<0.05. (b) Differentially expressed genes with at least 1.5-fold change. (c) Differentially expressed genes with at least twofold change.

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