Table 3 Univariate log-rank analyses for prognostic factors in 86 patients with follow-up

From: Prognostic implication of MET overexpression in myxofibrosarcomas: an integrative array comparative genomic hybridization, real-time quantitative PCR, immunoblotting, and immunohistochemical analysis

Parameters

Category

No. of patients with follow-up

OS

MeFS

   

No. of event

P-value

No. of event

P-value

Sex

Male

47

12

0.7680

15

0.3483

 

Female

39

10

 

15

 

Age

<60 years

32

7

0.1517

8

0.0333*

 

≥60 years

54

15

 

22

 

Location

Extremity

66

17

0.6290

23

0.5839

 

Axial

20

5

 

7

 

Tumor size

<6 cm

42

9

0.1762

10

0.0124*

 

≥6 cm

41

12

 

19

 

Tumor depth

Superficial

33

5

0.0321*

7

0.0162*

 

Deep

53

17

 

23

 

Myxoid area

≥75%

25

3

0.1381

4

0.0576

 

<75%

61

19

 

26

 

Necrotic area

<10%

59

13

0.1378

15

0.0010*

 

≥10%

27

9

 

15

 

Mitotic count

<20/10 HPFs

70

13

<0.0001*

18

<0.0001*

 

≥20/10 HPFs

16

9

 

12

 

FNCLCC grade

Grade 1

39

5

0.0437*

6

0.0030*

 

Grades 2 and 3

47

17

 

24

 

AJCC stage

Stages I and II

49

9

0.0354*

12

0.0056*

 

Stage III

34

12

 

17

 

MET expression

Low expression (<30%)

28

1

0.0032*

2

0.0007*

 

Overexpression (≥30%)

58

21

 

28

 
  1. *Statistically significant P-values.
  2. OS, overall survival; MeFS, metastasis-free survival.