Figure 5 | Modern Pathology

Figure 5

From: β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

Figure 5

β-Catenin nuclear expression is associated with poor survival. Kaplan–Meier curves for disease-free survival (a), metastasis-free survival (b) and overall survival (c) for 221 patients uniformly treated with anthracycline-based chemotherapy. Invasive breast carcinomas with β-catenin nuclear expression as defined by the 14/β-catenin clone (dark grey) are significantly associated with shorter metastasis-free survival and overall survival (P<0.05). A similar but non-significant trend was also observed with disease-free survival.

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