Figure 4

Kaplan–Meier curves plotting recurrence-free probability. Patients were stratified by level of MSMB expression into four subgroups (a), with different risk for biochemical recurrence. Black line: high intensity and fraction of positive tumor cells; dashed line: low intensity and high fraction; gray line: high intensity and low fraction; dotted line: low intensity and low fraction. The four subgroups were merged into two groups (b), either having high or low MSMB expression. Black line: high fraction of positive tumor cells; gray line: low fraction. Follow-up time ranged from 1–144 months. Only patients with complete follow-up data were included (n=2460).