Table 1 Immunohistochemical results
From: Cathepsin K expression in the spectrum of perivascular epithelioid cell (PEC) lesions of the kidney
Cathepsin K | HMB45 | CD68 (PG-M1) | CD68 (KP1) | MITF | Melan-A | α-SMA | |
|---|---|---|---|---|---|---|---|
Common angiomyolipoma | |||||||
Case 1 | + (90%) | + (10%) | + (10%) | + (50%) | + (60%) | + (30%) | + (60%) |
Case 2 | + (80%) | + (10%) | + (20%) | + (40%) | + (30%) | + (10%) | + (40%) |
Case 3 | + (90%) | + (5%) | + (10%) | + (50%) | Negative | + (50%) | + (40%) |
Case 4 | + (95%) | + (30%) | + (10%) | + (50%) | Negative | + (50%) | + (50%) |
Case 5 | + (85%) | + (10%) | + (5%) | + (60%) | Negative | + (10%) | + (50%) |
Case 6 | + (100%) | + (5%) | + (10%) | + (45%) | + (30%) | + (90%) | + (40%) |
Case 7 | + (90%) | + (5%) | + (5%) | + (50%) | + (10%) | + (80%) | + (50%) |
Case 8 | + (80%) | + (10%) | + (15%) | + (55%) | Negative | + (70%) | + (55%) |
Case 9 | + (90%) | + (10%) | + (10%) | + (30%) | + (5%) | + (50%) | n.a. |
Case 10 | + (90%) | + (10%) | + (20%) | + (50%) | + (20%) | + (30%) | + (70%) |
Case 11 | + (90%) | + (20%) | + (15%) | + (50%) | Negative | + (70%) | + (50%) |
Case 12 | + (85%) | + (5%) | n.a. | + (45%) | Negative | + (5%) | + (70%) |
Case 13 | + (90%) | + (10%) | + (10%) | + (50%) | Negative | + (20%) | + (60%) |
Case 14 | + (90%) | + (10%) | + (5%) | + (60%) | Negative | + (20%) | + (60%) |
Case 15 | + (100%) | + (15%) | + (10%) | + (40%) | + (80%) | n.a. | + (40%) |
Case 16 | + (90%) | + (15%) | + (10%) | + (40%) | + (10%) | + (90%) | + (70%) |
Case 17 | + (85%) | + (5%) | + (5%) | + (50%) | + (40%) | + (90%) | + (50%) |
Case 18 | + (90%) | Negative | + (10%) | + (30%) | Negative | + (40%) | + (30%) |
Case 19 | + (80%) | + (5%) | + (15%) | + (50%) | + (10%) | + (50%) | + (60%) |
Case 20 | + (85%) | + (10%) | + (10%) | + (30%) | + (60%) | + (50%) | n.a. |
Case 21 | + (90%) | + (15%) | + (10%) | + (45%) | Negative | + (70%) | + (50%) |
Case 22 | + (90%) | + (10%) | + (10%) | + (50%) | Negative | + (60%) | + (70%) |
Case 23 | + (90%) | + (15%) | + (15%) | + (60%) | + (10%) | + (40%) | + (60%) |
Case 24 | + (80%) | + (15%) | + (20%) | + (60%) | + (20%) | + (80%) | + (50%) |
Case 25 | + (90%) | + (20%) | + (10%) | n.a. | Negative | + (5%) | + (70%) |
Case 26 | + (100%) | + (5%) | + (10%) | + (50%) | Negative | + (40%) | + (50%) |
Case 27 | + (90%) | + (5%) | + (15%) | + (50%) | Negative | + (30%) | + (50%) |
Case 28 | + (90%) | + (10%) | + (5%) | + (55%) | Negative | + (30%) | + (40%) |
Case 29 | + (90%) | + (10%) | + (10%) | + (45%) | Negative | + (10%) | + (70%) |
Case 30 | + (100%) | + (20%) | + (20%) | + (70%) | + (30%) | + (20%) | + (30%) |
Case 31 | + (80%) | + (10%) | + (10%) | + (40%) | + (50%) | + (60%) | + (60%) |
Common angiomyolipoma (biopsy) | |||||||
Case 1 | + (90%) | + (10%) | n.a. | n.a. | n.a. | n.a. | n.a. |
Case 2 | + (80%) | + (10%) | n.a. | n.a. | n.a. | n.a. | n.a. |
Case 3 | + (90%) | + (5%) | n.a. | n.a. | n.a. | n.a. | n.a. |
Lipoma-like angiomyolipoma | |||||||
Case 1 | + (90%) | + (10%) | + (10%) | + (50%) | + (10%) | + (40%) | + (10%) |
Case 2 | + (85%) | + (10%) | + (5%) | + (40%) | Negative | + (50%) | + (10%) |
Case 3 | + (90%) | n.a. | + (10%) | + (30%) | Negative | + (60%) | + (20%) |
Case 4 | + (100%) | + (10%) | + (20%) | + (50%) | + 10%) | + (20%) | + (5%) |
Case 5 | + (90%) | + (5%) | + (15%) | + (60%) | Negative | + (10%) | + (10%) |
Leiomyoma-like angiomyolipoma | |||||||
Case 1 | + (90%) | + (10%) | + (10%) | + (50%) | + (10%) | + (60%) | + (70%) |
Case 2 | + (90%) | + (5%) | + (20%) | + (60%) | Negative | + (90%) | + (50%) |
Case 3 | + (80%) | + (10%) | + (5%) | + (60%) | Negative | + (40%) | + (80%) |
Case 4 | + (100%) | n.a. | + (10%) | + (40%) | + (40%) | + (10%) | + (80%) |
Case 5 | + (90%) | + (10%) | + (10%) | + (50%) | Negative | Negative | + (60%) |
Case 6 | + (85%) | Negative | + (10%) | + (45%) | Negative | + (70%) | + (70%) |
Case 7 | + (90%) | + (10%) | + (20%) | + (50%) | Negative | n.a. | + (80%) |
Case 8 | + (100%) | + (5%) | + (10%) | + (50%) | + (20%) | + (40%) | + (60%) |
Case 9 | + (80%) | + (5%) | + (15%) | + (55%) | + (50%) | + (80%) | + (60%) |
Case 10 | + (90%) | + (10%) | n.a. | + (45%) | Negative | + (80%) | + (50%) |
Case 11 | + (100%) | + (15%) | + (10%) | + (70%) | + (10%) | + (20%) | n.a. |
Case 12 | + (90%) | + (20%) | + (15%) | + (50%) | Negative | + (40%) | + (80%) |
Case 13 | + (100%) | + (10%) | + (15%) | + (40%) | n.a. | + (90%) | + (50%) |
Case 14 | + (80%) | Negative | + (5%) | + (40%) | + (60%) | + (50%) | + (80%) |
Case 15 | + (90%) | + (15%) | + (20%) | + (50%) | + (30%) | + (5%) | + (70%) |
Microscopic angiomyolipoma | |||||||
Case 1 | + (100%) | + (10%) | + (20%) | + (50%) | + (20%) | + (10%) | + (40%) |
Case 2 | + (90%) | + (10%) | + (5%) | + (80%) | + (10%) | + (40%) | + (70%) |
Case 3 | + (90%) | + (10%) | + (10%) | + (50%) | + (60%) | + (30%) | + (30%) |
Case 4 | + (85%) | + (5%) | + (10%) | + (50%) | Negative | + (5%) | + (80%) |
Case 5 | + (100%) | + (5%) | + (10%) | + (60%) | Negative | + (90%) | n.a. |
Case 6 | + (100%) | + (10%) | + (15%) | + (60%) | + (10%) | + (90%) | + (50%) |
Case 7 | + (90%) | + (10%) | + (15%) | + (70%) | Negative | + (50%) | + (50%) |
Case 8 | + (90%) | + (15%) | + (20%) | + (50%) | + (5%) | + (80%) | + (30%) |
Case 9 | + (90%) | + (5%) | + (20%) | + (55%) | + (10%) | + (30%) | + (70%) |
Case 10 | + (85%) | + (15%) | + (20%) | + (60%) | Negative | + (80%) | + (30%) |
Case 11 | + (100%) | + (10%) | + (5%) | + (50%) | Negative | + (20%) | + (40%) |
Case 12 | + (90%) | + (5%) | + (15%) | n.a. | + (40%) | + (5%) | + (70%) |
Case 13 | + (100%) | + (20%) | + (10%) | + (50%) | + (5%) | + (10%) | + (50%) |
Case 14 | + (100%) | + (5%) | + (20%) | + (45%) | Negative | + (90%) | + (30%) |
Case 15 | + (90%) | Negative | + (10%) | + (40%) | + (30%) | + (70%) | + (30%) |
Intraglomerular lesions | |||||||
Case 1 | + (70%) | Negative | n.a. | n.a. | Negative | Negative | Negative |
Case 2 | + (60%) | Negative | n.a. | n.a. | Negative | Negative | Negative |
Case 3 | + (70%) | Negative | n.a. | n.a. | Negative | Negative | + (5%) |
Case 4 | + (90%) | Negative | n.a. | n.a. | Negative | Negative | + (5%) |
Case 5 | + (90%) | Negative | n.a. | n.a. | Negative | Negative | + (5%) |
Oncocytoma-like angiomyolipomas | |||||||
Case 1 | + (90%) | + (10%) | + (15%) | + (60%) | + (30%) | + (10%) | + (10%) |
Case 2 | + (90%) | + (10%) | + (2%) | + (2%) | Negative | + (10%) | + (70%) |
Angiomyolipomas with epithelial cysts | |||||||
Case 1 | |||||||
Leiomyoma-like AML | + (90%) | + (20%) | + (2%) | + (2%) | + (10%) | + (40%) | + (30%) |
Epithelioid AML | + (90%) | + (10%) | + (2%) | + (2%) | Negative | + (90%) | + (40%) |
Epithelium of the cysts | Negative | Negative | Negative | Negative | Negative | Negative | Negative |
‘Cambium-like’ layer | + (90%) | + (5%) | Negative | Negative | + (50%) | + (5%) | + (30%) |
Case 2 | |||||||
Leiomyoma-like AML | + (90%) | + (40%) | + (10%) | + (30%) | + (40%) | + (30%) | + (60%) |
Epithelium of the cysts | Negative | Negative | Negative | Negative | Negative | Negative | Negative |
‘Cambium-like’ layer | + (90%) | + (40%) | + (10%) | + (30%) | + (30%) | + (50%) | + (40%) |
Epithelioid angiomyolipomas | |||||||
Case 1 | + (90%) | + (70%) | + (40%) | + (50%) | + (30%) | + (40%) | + (10%) |
Case 2 | + (100%) | + (80%) | + (50%) | + (90%) | + (10%) | + (30%) | + (10%) |
Case 3 | + (95%) | + (80%) | + (80%) | + (50%) | + (40%) | + (10%) | Negative |
Case 4 | + (90%) | + (100%) | + (60%) | + (80%) | Negative | + (5%) | + (20%) |
Case 5 | + (100%) | + (80%) | + (80%) | + (60%) | Negative | + (90%) | + (5%) |
Case 6 | + (100%) | + (40%) | + (50%) | + (80%) | + (80%) | + (50%) | Negative |
Case 7 | + (95%) | + (80%) | + (40%) | + (50%) | Negative | + (50%) | Negative |
Case 8 | + (90%) | + (80%) | + (70%) | + (60%) | + (50%) | + (30%) | Negative |
Lymphangioleiomyomatosis of the renal sinus | |||||||
Case 1 | + (90%) | + (80%) | Negative | + (90%) | + (30%) | + (50%) | + (60%) |
