Figure 3 | Modern Pathology

Figure 3

From: Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes

Figure 3

Comparison of methylation frequencies (a) and levels (b) of CpG island loci between ER-negative and ER-positive breast cancers. Methylation levels are given as means and SE (error bar). (a) Methylation frequencies of APC, DLEC1, GSTP1, HOXA1, RASSF1A, RUNX3, SCGB3A1, SFRP1, and TMEFF2 are significantly higher in ER-positive than in ER-negative tumors. (b) Methylation levels are significantly higher in ER-positive than in ER-negative tumors for APC, DLEC1, HOXA1, RASSF1A, RUNX3, SCGB3A1, and SFRP1, but not for GSTP1 and TMEFF2.

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