Figure 2

H&E staining (a), immunohistochemistry for MLH1 (b) and PMS2 (c) in a patient with a germline splicing mutation in MLH1 showing heterogeneous loss of expression of MLH1 and complete loss of expression of PMS2 in adenoma cells.

H&E staining (a), immunohistochemistry for MLH1 (b) and PMS2 (c) in a patient with a germline splicing mutation in MLH1 showing heterogeneous loss of expression of MLH1 and complete loss of expression of PMS2 in adenoma cells.